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Longitudinal analysis of group A Streptococcus emm types and emm clusters in a high prevalence setting reveals past infection does not prevent future infection.

Longitudinal analysis of group A Streptococcus emm types and emm clusters in a high prevalence setting reveals past infection does not prevent future infection.

Group A Streptococcus (GAS) is a pathogen of worldwide significance, however regardless of the ubiquity of GAS infections, there stays incomplete understanding of the connection between an infection, colonization and immunity. The M protein, encoded by the emm gene, is a significant virulence issue and vaccine candidate and kinds the idea of plenty of classification programs. Longitudinal patterns of emm varieties collected from 457 Fijian schoolchildren over a ten-month interval had been analyzed. No proof of tissue tropism was noticed, and there was no obvious selective stress or constraint of emm varieties. Patterns of emm sort acquisition recommend restricted, if…
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